Before we started out writing articles for this blogsite, we decided to check out the competition, so to say. We checked out similar websites that also dealt with Propecia and we wanted to see if there is something those websites missed and that would be of interest to people who might be considering using Propecia. One thing that we found that those websites often omitted was the explanation as to how Propecia works. It may be laziness or it may be a misconception that no one would be interested in this. We believe that people are interested in this as it gives them more faith in a medication when they know exactly how it works. It also prevents people from believing in scam products that claim to do the same thing Propecia does without explaining how they do this. So, here it is.
The mechanism of action of Propecia is hidden in the name of the class it belongs to – 5-alpha reductase inhibitors. The inhibitor part stands for preventing the functioning of something, in this case 5-alpha reductase. However, in order to understand how Propecia works and why this is so important, we need to explain what 5-alpha reductase does and how it is involved in hair loss. The story goes like this.
Testosterone is a male hormone and in men it is produced both in testicles and adrenal glands. It is then transported throughout the body by sex hormone binding globulin, or SHBG. In different parts of the body, testosterone is released from SHBG and it enters different cells there in order to play a certain role. However, in some of the tissues in the body, testosterone is converted in another hormone called dihydrotestosterone, from here on DHT.
DHT is a much more potent androgen than testosterone and it has a more pronounced androgenic activity. This activity is manifested differently in different areas in the body. For instance, in the prostate, it leads to enlargement of the tissue, which as a result can have enlarged prostate. In the scalp tissue, it causes deterioration of the follicles of the hair, reducing their life span and making the hair fall out more rapidly, while also reducing further hair growth.
In order for this conversion from testosterone to DHT to happen, an enzyme is necessary and the name of this enzyme is 5-alpha reductase. What Propecia does is it binds to this enzyme and thus prevents testosterone from binding to it, which would ultimately lead to its conversion into DHT. Basically, imagine if testosterone was Clark Kent and 5-alpha reductase was the phone booth where he changes into Superman. Propecia acts as a person that will occupy the phone booth and prevent Clark Kent from turning into Superman.